P4HB Rabbit polyclonal antibody

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£152.00

SKU:: A0709
Zusätzliche Namen:: CLCRP1|DSI|ERBA2L|GIT|P4HB|P4Hbeta|PDI|PDIA1|PHDB|PO4DB|PO4HB|PROHB
Anwendung:: ELISA, WB, IHC-P, IF, ICC
Molekulargewicht:: 57kda
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: PESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQKAVKDEL
Uniprot:: P07237
Synonyme:: cellular thyroid hormone-binding protein;CLCRP1;collagen prolyl 4-hydroxylase beta;DSI;ERBA2L;GIT;glutathione-insulin transhydrogenase;P4Hbeta;p55;PDI;PDIA1;PHDB;PO4DB;PO4HB;procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide;PROHB;Prolyl 4-hydroxylase subunit beta;prolyl 4-hydroxylase, beta polypeptide;protein disulfide isomerase family A, member 1;protein disulfide isomerase-associated 1;protein disulfide isomerase/oxidoreductase;protein disulfide-isomerase;protocollagen hydroxylase;testicular secretory protein Li 32;thyroid hormone-binding protein p55
Weitere Details:: This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.

Versandbedingungen:: Blue Ice