SOCS3 Rabbit polyclonal antibody

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£151.00

SKU:: A0694
Zusätzliche Namen:: ATOD4|CIS3|Cish3|SOCS-3|SOCS3|SSI-3|SSI3
Anwendung:: ELISA, WB, IHC-P, IF, ICC
Molekulargewicht:: 30 kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Uniprot:: O14543
Synonyme:: ATOD4;CIS3;Cish3;cytokine-inducible SH2 protein 3;SOCS-3;SSI-3;SSI3;STAT-induced STAT inhibitor 3;suppressor of cytokine signaling 3
Weitere Details:: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.