TNFRSF6B Rabbit polyclonal antibody

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£152.00

SKU:: A0649
Zusätzliche Namen:: DCR3|DJ583P15.1.1|M68|M68E|TNFRSF6B|TR6
Anwendung:: ELISA, WB
Molekulargewicht:: 33kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: PLSTRVPGAEECERAVIDFVAFQDISIKRLQRLLQALEAPEGWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMPGLERSVRERFLPVH
Uniprot:: O95407
Synonyme:: DCR3;Decoy receptor 3;decoy receptor 3 variant 1;decoy receptor 3 variant 2;decoy receptor for Fas ligand;DJ583P15.1.1;M68;M68E;TR6;tumor necrosis factor receptor superfamily member 6B;tumor necrosis factor receptor superfamily, member 6b, decoy
Weitere Details:: This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript.