SOD1 Rabbit polyclonal antibody

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£152.00

SKU:: A0274
Zusätzliche Namen:: ALS|ALS1|HEL-S-44|homodimer|hSod1|IPOA|SOD|SOD1|STAHP
Anwendung:: ELISA, WB, IHC-P, IF, ICC, IP
Molekulargewicht:: 16-18kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: ATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ
Uniprot:: P00441
Synonyme:: ALS;ALS1;Cu/Zn superoxide dismutase;epididymis secretory protein Li 44;HEL-S-44;homodimer;hSod1;indophenoloxidase A;IPOA;SOD;SOD, soluble;STAHP;superoxide dismutase [Cu-Zn];Superoxide dismutase 1;superoxide dismutase 1, soluble;superoxide dismutase, cystolic
Weitere Details:: The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. In addition, this protein contains an antimicrobial peptide that displays antibacterial, antifungal, and anti-MRSA activity against E. coli, E. faecalis, S. aureus, S. aureus MRSA LPV+, S. agalactiae, and yeast C. krusei. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

Versandbedingungen:: Blue Ice