CDK10 Antibody (pThr196): ATTO 390
Produktgrößen
100 ul
£512,00
SPC-939D-A390-100UL
Über dieses Produkt
- SKU:
- SPC-939D-A390
- Zusätzliche Namen:
- CDK10, Cyclin-dependent kinase 10, Cell division protein kinase 10, CDC2-related protein kinase, CDK10_HUMAN, PISSLRE, Serine/threonine protein kinase PISSLRE
- Anwendung:
- Antibody Microarray, Western Blot
- Buffer:
- 640.91mM DMSO, 136.36 mM Ethanolamine, 126.89 mM chlorides, 9.09mM phosphates, 9.09mM NaHCO3
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Klonalität:
- Polyclonal
- Konjugat:
- ATTO 390
- Weitere Details:
- CDK10 is a serine/threonine kinase involved in regulating the G2-M phase of the cell cycle. Although historically studied in the context of cellular proliferation, recent evidence suggests CDK10 may also influence neuronal differentiation, cytoskeletal dynamics, and transcriptional regulation. Phosphorylation at threonine 196 (pThr196) is critical for CDK10 activation and function. In neurons, dysregulation of CDK10 activity may disrupt cell cycle re-entry, a pathological hallmark observed in several neurodegenerative diseases, including Alzheimer's disease. As a modulator of both cell cycle and transcriptional machinery, CDK10 represents a novel candidate for investigating the molecular underpinnings of neurodegeneration.
- Host:
- Rabbit
- Immunogen:
- A phospho-specific peptide corresponding to residues surrounding Thr196 of human CDK10 (AA193-199)
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Spezifität:
- Detects 41.038 kDa.
- Lagerbedingungen:
- See Manual
- Hersteller:
- StressMarq Biosciences
- Typ:
- Antibody: Polyclonal Antibody