Choline Acetyltransferase Antibody: ATTO 594
Produktgrößen
100 ug
£511,00
SPC-706D-A594-100UG
Über dieses Produkt
- SKU:
- SPC-706D-A594
- Zusätzliche Namen:
- CHAT, Choline acetyltransferase, Acetyl-CoA choline O-acetyltransferase, Choline acetylase, CLAT_HUMAN, CMS1A
- Anwendung:
- Immunocytochemistry, Immunofluorescence, Western Blot
- Buffer:
- 640.91mM DMSO, 136.36 mM Ethanolamine, 126.89 mM chlorides, 9.09mM phosphates, 9.09mM NaHCO3
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Klonalität:
- Polyclonal
- Konjugat:
- ATTO 594
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Choline acetyltransferase (ChAT) catalyzes the synthesis of acetylcholine (ACh), a neurotransmitter essential for motor control, memory, and autonomic function. ChAT is selectively expressed in cholinergic neurons, making it a reliable marker for cholinergic system integrity. Loss of ChAT activity is a hallmark of several neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Down syndrome. Reduced ChAT expression correlates with cognitive decline and impaired synaptic transmission in affected brain regions. As a neuron-specific enzyme with a direct role in neurotransmitter synthesis, ChAT is both a diagnostic marker and a therapeutic target in disorders characterized by cholinergic dysfunction.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide from the N-terminal to the mid-protein of human Choline O-Acetyltrasferase
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Spezifität:
- Predicted molecular weight at ~82.5kDa. Observed molecular weights between 68-70kDa.
- Lagerbedingungen:
- See Manual
- Hersteller:
- StressMarq Biosciences
- Typ:
- Antibody: Polyclonal Antibody