DENND4C Antibody: ATTO 390
Produktgrößen
100 ug
£578,00
SMC-610D-A390-100UG
Über dieses Produkt
- SKU:
- SMC-610D-A390
- Zusätzliche Namen:
- DENN domain-containing protein 4C
- Anwendung:
- Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
- Buffer:
- 640.91mM DMSO, 136.36 mM Ethanolamine, 126.89 mM chlorides, 9.09mM phosphates, 9.09mM NaHCO3
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- translate.label.attr.clone:
- 3E8
- Klonalität:
- Monoclonal
- Konjugat:
- ATTO 390
- Konzentration:
- 1 mg/ml
- Weitere Details:
- DENND4C is a guanine nucleotide exchange factor (GEF) for Rab10, a small GTPase involved in vesicle trafficking and membrane recycling. DENND4C regulates GLUT4 translocation and interacts with the retromer complex, linking it to endosomal sorting and cellular metabolism. Mutations in DENND4C have been associated with neurodevelopmental syndromes such as Alkuraya-Kucinskas and Koolen-De Vries, suggesting a broader role in brain development and function. Its involvement in membrane trafficking pathways positions DENND4C as a candidate for investigation in neurodegenerative diseases characterized by endolysosomal dysfunction.
- Host:
- Mouse
- Immunogen:
- Full Length Human Recombinant Dennd4c protein
- Isotyp:
- IgG1
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Spezifität:
- Detects ~213 kDa.
- Lagerbedingungen:
- See Manual
- Hersteller:
- StressMarq Biosciences
- Typ:
- Antibody: Monoclonal Antibody