Dityrosine Antibody, Clone 7D4: Biotin
Produktgrößen
100 ug
£598,00
SMC-520D-BI-100UG
Über dieses Produkt
- SKU:
- SMC-520D-BI
- Zusätzliche Namen:
- Dityrosine, Dityrosine (DT), DT, DY
- Anwendung:
- ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
- Buffer:
- 136.36mM Ethanolamine, 133.23 mM Chlorides, 9.55mM Phosphates, 9.55mM Sodium Bicarbonate
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- translate.label.attr.clone:
- 7D4
- Klonalität:
- Monoclonal
- Konjugat:
- Biotin
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Dityrosine is a stable, covalent cross-link formed between tyrosine residues in proteins under oxidative stress. It is generated by reactive oxygen species (ROS) such as hydroxyl radicals and catalyzed by peroxidases and UV radiation. As a biomarker of protein oxidation, dityrosine reflects cumulative oxidative damage in tissues. In the brain, elevated dityrosine levels are associated with protein aggregation, mitochondrial dysfunction, and neuroinflammation-features common to Alzheimer's, Parkinson's, and other neurodegenerative diseases. Monitoring dityrosine formation provides insight into oxidative stress burden and may aid in evaluating antioxidant therapies and disease progression in neurodegenerative research.
- Host:
- Mouse
- Immunogen:
- Synthetic Dityrosine conjugated to Keyhole Limpet Hemocyanin (KLH).
- Isotyp:
- IgG1
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Wide/Non-species Specific
- Versandbedingungen:
- Blue Ice
- Spezifität:
- Specific for dityrosine modified proteins. Does not cross-react with 3,5-dibromotyrosine or bromotyrosine modified proteins.
- Lagerbedingungen:
- See Manual
- Hersteller:
- StressMarq Biosciences
- Typ:
- Antibody: Monoclonal Antibody