DMPO Antibody, Clone N1664A: PerCP
Produktgrößen
100 ug
£521,00
SMC-189D-PCP-100UG
Über dieses Produkt
- SKU:
- SMC-189D-PCP
- Zusätzliche Namen:
- 5,5-dimethyl-1-pyrroline N-oxide, 5,5-dimethyl-2-(8-octanoic acid)-1-pyrroline N-oxide, DMPO nitrone adduct, 55 dimethyl 1 pyrroline N oxide nitrone adduct
- Anwendung:
- Antibody Microarray, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- 95.46mM Phosphate, 2.48mM MES and 2mM EDTA
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- translate.label.attr.clone:
- N1664A
- Klonalität:
- Monoclonal
- Konjugat:
- PerCP
- Konzentration:
- 1 mg/ml
- Weitere Details:
- DMPO (5,5-dimethyl-1-pyrroline N-oxide) is a widely used spin trap compound for detecting free radicals and reactive oxygen species (ROS) in biological systems. Its low toxicity and favorable pharmacokinetics make it ideal for in vivo and in vitro studies of oxidative stress-a central mechanism in neurodegenerative diseases such as Alzheimer's, Parkinson's, and ALS. DMPO forms stable nitrone adducts with protein and DNA radicals, enabling precise identification of oxidative modifications that contribute to neuronal damage. These adducts serve as biomarkers for radical-induced injury, offering insights into disease progression and therapeutic response. However, the presence of nitric oxide and related reactive nitrogen species can interfere with DMPO quantification, necessitating careful experimental design. By enabling real-time detection of oxidative stress at the molecular level, DMPO supports the development of antioxidant strategies and enhances understanding of redox imbalance in neurodegeneration.
- Host:
- Mouse
- Immunogen:
- 5,5-dimethyl-2-(8-octanoic acid)-1-pyrrolone-N-oxide conjugated to Ovalbumin
- Isotyp:
- IgG1
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Wide/Non-species Specific
- Versandbedingungen:
- Blue Ice
- Spezifität:
- Recognizes DMPO, DMPO-octanoic acid, DMPO-protein adducts and DMPO-DNA adducts. Does not cross react with non-adducted proteins or DNA.
- Lagerbedingungen:
- See Manual
- Hersteller:
- StressMarq Biosciences
- Typ:
- Antibody: Monoclonal Antibody