HSP70 ELISA Kit (High-Sensitivity)
Produktgrößen
96 wells
£868,00
SKT-108-96WELLS
Über dieses Produkt
- SKU:
- SKT-108
- Zusätzliche Namen:
- HSP70 1, HSP70 2, HSP70.1, HSP72, HSPA1, HSPA1A, HSPA1B
- CE/IVD:
- RUO
- Weitere Details:
- Heat Shock Protein 70 (HSP70) is a highly conserved molecular chaperone encoded by a multigene family and expressed across all major cellular compartments, including the cytosol, mitochondria, and endoplasmic reticulum. HSP70 binds to nascent and misfolded proteins, preventing aggregation and facilitating proper folding through ATP-dependent conformational changes. In neuroscience, HSP70 plays a critical role in maintaining proteostasis under stress conditions. Its ability to stabilize unfolded proteins is especially relevant in neurodegenerative diseases such as Alzheimer's, Parkinson's, and ALS, where protein misfolding and aggregation are central to pathogenesis. HSP70's dynamic binding and release cycles are essential for neuronal survival, synaptic function, and cellular resilience. By modulating HSP70 activity, researchers aim to enhance the brain's natural defense mechanisms against proteotoxic stress, making it a promising therapeutic target in neurodegeneration.
- Format:
- Colorimetric
- Immunogen:
- HSP70 ELISA Kit (High-Sensitivity)
- Physischer Zustand:
- Cell Lysate, Plasma, Tissue
- Reichweite:
- 0.42 - 27 ng/ml
- Reaktivitäten:
- Canine, Human, Mouse, Non-human Primate, Rat
- Empfindlichkeit:
- 0.038 ng/ml
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C, -20[o]C
- Hersteller:
- StressMarq Biosciences
- Typ:
- Assay Kits: ELISAs