Carfilzomib
Produktgrößen
5 mg
£151,00
SIH-544-5MG
25 mg
£389,00
SIH-544-25MG
Über dieses Produkt
- SKU:
- SIH-544
- Zusätzliche Namen:
- (A AlphaS)-A Alpha-[[2-(4-morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]-L-phenylalaninamide, PR-17, Carfilzomib, Kyprolis, Carfilzomib (PR-171), PR-171, UNII-72X6E3J5AR
- CAS Number:
- 868540-17-4
- CE/IVD:
- RUO
- Weitere Details:
- Carfilzomib is an irreversible proteasome inhibitor that selectively targets the chymotrypsin-like activity of the 20S proteasome. While primarily developed as an anticancer agent, Carfilzomib has relevance in neurodegenerative disease research due to its impact on protein homeostasis. By modulating the ubiquitin-proteasome system, Carfilzomib helps elucidate mechanisms of protein aggregation and clearance, which are central to diseases like Alzheimer's, Parkinson's, and ALS. Its role in inducing apoptosis and cell cycle arrest also provides insights into neuronal vulnerability and stress responses.
- Molekulargewicht:
- 719.9
- Reinheit:
- >98%
- Versandbedingungen:
- Ambient
- Quelle:
- Synthetic
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- StressMarq Biosciences
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Datenblatt des Herstellers:https://www.stressmarq.com/products/small-molecules/inhibitor/carfilzomib-sih-544/