Bexarotene
Produktgrößen
10 mg
£145,00
SIH-535-10MG
100 mg
£216,00
SIH-535-100MG
Über dieses Produkt
- SKU:
- SIH-535
- Zusätzliche Namen:
- SR 11247, Targretin, 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid
- CAS Number:
- 153559-49-0
- CE/IVD:
- RUO
- Weitere Details:
- Bexarotene is a highly potent and selective retinoid X receptor (RXR) agonist, originally developed as an antineoplastic agent for cutaneous T-cell lymphoma. In neuroscience, Bexarotene has garnered significant attention for its ability to enhance the clearance of soluble B Beta-amyloid and improve cognitive function in animal models of Alzheimer's disease. It has also been shown to reverse apoE4-driven brain pathology and behavioral deficits, highlighting its potential in targeting genetic risk factors for neurodegeneration. By modulating lipid metabolism, inflammation, and gene expression, Bexarotene represents a promising therapeutic avenue for neurodegenerative diseases. Its dual role in oncology and neurology underscores its versatility and scientific impact.
- Molekulargewicht:
- 348.5
- Reinheit:
- >98%
- Versandbedingungen:
- Ambient
- Quelle:
- Synthetic
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- StressMarq Biosciences
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Datenblatt des Herstellers:https://www.stressmarq.com/products/small-molecules/agonist/bexarotene-sih-535/