C16
Produktgrößen
5 mg
£145,00
SIH-498-5MG
25 mg
£395,00
SIH-498-25MG
Über dieses Produkt
- SKU:
- SIH-498
- Zusätzliche Namen:
- Imidazolo-oxindole PKR inhibitor C16, 6,8-Dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one
- CAS Number:
- 608512-97-6
- CE/IVD:
- RUO
- Weitere Details:
- C16 is a derivative of imidazolo-oxindole and functions as a selective inhibitor of RNA-dependent protein kinase (PKR), a key regulator of cellular stress responses. By targeting the ATP-binding site of PKR, C16 effectively blocks the PKR/eIF2A Alpha signaling pathway, which is implicated in apoptosis and neuroinflammation. In neurodegenerative disease research, C16 has gained attention for its potential to mitigate neuronal cell death and reduce inflammatory cascades associated with conditions such as Alzheimer's and Parkinson's disease. Its ability to modulate stress-induced translational control makes it a valuable tool for studying neuroprotective mechanisms and therapeutic interventions in central nervous system disorders.
- Molekulargewicht:
- 268.3
- Reinheit:
- ≥98%
- Versandbedingungen:
- Ambient
- Quelle:
- Synthetic
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- StressMarq Biosciences
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Datenblatt des Herstellers:https://www.stressmarq.com/products/small-molecules/inhibitor/c16-sih-498/