AS 041164
Produktgrößen
10 mg
£149,00
SIH-433-10MG
50 mg
£448,00
SIH-433-50MG
Über dieses Produkt
- SKU:
- SIH-433
- Zusätzliche Namen:
- NSC31098, 5-Benzo[1,3]dioxol-5-ylmethylene-thiazolidine-2,4-dione
- CAS Number:
- 6318-41-8
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Weitere Details:
- AS 041164 is a selective inhibitor of the PI3KG Gamma isoform, a key regulator of immune cell signaling and migration. In neuroscience, PI3KG Gamma has been implicated in neuroinflammatory responses and microglial activation, processes that contribute to the progression of neurodegenerative diseases. By blocking PI3KG Gamma activity, AS 041164 can modulate leukocyte trafficking and reduce neuroinflammation, making it a valuable tool for studying immune-mediated mechanisms in conditions such as multiple sclerosis, Alzheimer's disease, and Parkinson's disease. Its ability to inhibit neutrophil migration further supports its application in models of neurovascular inflammation and blood-brain barrier dysfunction.
- Molekulargewicht:
- 249.2
- Reinheit:
- ≥98%
- Versandbedingungen:
- Ambient
- Quelle:
- Synthetic
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- StressMarq Biosciences
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Datenblatt des Herstellers:https://www.stressmarq.com/products/small-molecules/inhibitor/as-041164-sih-433/