Doxorubicin Hydrochloride
Produktgrößen
10 mg
£211,00
SIH-390-10MG
50 mg
£606,00
SIH-390-50MG
Über dieses Produkt
- SKU:
- SIH-390
- Zusätzliche Namen:
- Adriamycin
- CAS Number:
- 25316-40-9
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Weitere Details:
- Doxorubicin Hydrochloride is a DNA-intercalating chemotherapeutic agent known for its broad-spectrum anticancer activity. In neuroscience, Doxorubicin is used to model neurotoxicity and investigate mechanisms of neuronal damage, particularly in studies of chemotherapy-induced cognitive impairment ("chemo brain"). It induces apoptosis by inhibiting topoisomerase II and disrupting DNA replication and transcription. Doxorubicin also triggers oxidative stress and mitochondrial dysfunction-key features of neurodegenerative diseases. Although its clinical use is limited by systemic toxicity, including hematologic and cardiac effects, its ability to induce autophagy and cell death pathways makes it a valuable tool for studying neuronal stress responses and neurodegeneration in vitro and in vivo.
- Molekulargewicht:
- 580
- Reinheit:
- >98%
- Versandbedingungen:
- Ambient
- Quelle:
- Synthetic
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- StressMarq Biosciences
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Datenblatt des Herstellers:https://www.stressmarq.com/products/small-molecules/inducer/doxorubicin-hydrochloride-sih-390/