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Produktgrößen
5 mg
SIH-354-5MG
25 mg
SIH-354-25MG
Über dieses Produkt
SKU:
SIH-354
Zusätzliche Namen:
(E)-N-[4-(1-benzoylpiperidin-4-yl)butyl]-3-(pyridin-3-yl)acrylamide, FK866 hydrochloride hydrate, K22.175
CAS Number:
658084-64-1
CE/IVD:
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Weitere Details:
FK-866 HCl is a potent inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme involved in NAD⁺ biosynthesis. In neuroscience, FK-866 is used to study the role of NAD⁺ metabolism in neuronal survival, energy homeostasis, and neuroinflammation. NAD⁺ depletion induced by FK-866 leads to mitochondrial dysfunction and cell death, providing a model for investigating neurodegenerative mechanisms. Its application extends to exploring therapeutic strategies that target metabolic resilience and oxidative stress in neurodegenerative diseases.
Molekulargewicht:
428
Reinheit:
>98%
Versandbedingungen:
Ambient
Quelle:
Synthetic
Lagerbedingungen:
-20[o]C
Hersteller:
StressMarq Biosciences
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors