C-646
Produktgrößen
5 mg
£192,00
SIH-350-5MG
25 mg
£631,00
SIH-350-25MG
Über dieses Produkt
- SKU:
- SIH-350
- Zusätzliche Namen:
- 4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]- 4,5-dihydro-3-methyl-5-oxo-1Hpyrazol- 1-yl]benzoic acid
- CAS Number:
- 328968-36-1
- CE/IVD:
- RUO
- Weitere Details:
- C-646 is a potent and selective inhibitor of the histone acetyltransferase p300/CBP, with a Ki of 400 nM. In neuroscience, C-646 has been shown to enhance synaptic plasticity and memory formation, particularly in fear extinction paradigms. It also promotes tau deacetylation, thereby reducing levels of pathogenic phosphorylated tau (p-tau), a hallmark of Alzheimer's disease. These properties position C-646 as a promising epigenetic modulator for neurodegenerative disease research, offering insights into chromatin remodeling and transcriptional regulation in neuronal health and disease.
- Molekulargewicht:
- 445.4
- Reinheit:
- >98%
- Versandbedingungen:
- Ambient
- Quelle:
- Synthetic
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- StressMarq Biosciences
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Datenblatt des Herstellers:https://www.stressmarq.com/products/small-molecules/inhibitor/c-646-sih-350/