Apicidin
Produktgrößen
1 mg
£144,00
SIH-346-1MG
5 mg
£384,00
SIH-346-5MG
Über dieses Produkt
- SKU:
- SIH-346
- Zusätzliche Namen:
- (3S,6S,9S,15aR)-9-[(2S)-2-Butanyl]-6-[(1-methoxy-1H-indol-3-yl)methyl]-3-(6-oxooctyl)octahydro-2H-pyrido[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10(3H,12H)-tetrone; Cyclo(N-O-methyl-L-tryptophanyl-L Lisoleucinyl-Dpipecolinyl-L-2-amino-8-oxodecanoyl)
- CAS Number:
- 183506-66-3
- CE/IVD:
- RUO
- Weitere Details:
- Apicidin is a cyclopeptide inhibitor of histone deacetylases (HDACs), known for its ability to induce transcriptional activation and inhibit cell proliferation. While it has been primarily studied in oncology for its antiproliferative effects, Apicidin's role in epigenetic modulation has implications for neuroscience. HDAC inhibitors like Apicidin are being explored for their potential to enhance synaptic plasticity, memory formation, and neuroprotection. By altering chromatin structure and gene expression, Apicidin may influence pathways involved in neurodegenerative diseases such as Alzheimer's and Huntington's. Its ability to decrease HIF1A Alpha protein levels and modulate transcriptional activity further supports its relevance in cellular stress responses, making it a candidate for broader neurological research.
- Molekulargewicht:
- 623.8
- Reinheit:
- >98%
- Versandbedingungen:
- Ambient
- Quelle:
- Synthetic
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- StressMarq Biosciences
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Datenblatt des Herstellers:https://www.stressmarq.com/products/small-molecules/inhibitor/apicidin-sih-346/