FRP-4, soluble
Produktgrößen
5ug
£178,82
S01-075S-5UG
Über dieses Produkt
- SKU:
- S01-075S
- Zusätzliche Namen:
- Secreted frizzled-related protein 4, DDC-4 (rat homologue)
- translate.label.attr.clone:
- (#9F40)
- Weitere Details:
- HB-EGF is an EGF related growth factor that signals through the EGF receptor, and stimulates the proliferation of smooth muscle cells (SMC), fibroblasts, epithelial cells, and keratinocytes. HB-EGF is expressed in numerous cell types and tissues, including vascular endothelial cells and SMC, macrophages, skeletal muscle, keratinocytes, and certain tumor cells. The ability of HB-EGF to specifically bind heparin and heparin sulfate proteoglycans is distinct from other EGF-like molecules, and may be related to the enhanced mitogenic activity, relative to EGF, that HB-EGF exerts on smooth muscle cells. The human HB-EGF gene encodes a 208 amino acid transmembrane protein, which can be proteolytically cleaved to produce soluble HB-EGF. Recombinant human HB-EGF is a 9.7 kDa protein containing 86 amino acid residues, corresponding to the extra-cellular EGF-like and heparin binding domains of the full length HB-EGF protein.
- Formulierung:
- lyophilized
- Host:
- Rat
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Room Temperature