IL-17E
Produktgrößen
5ug
£178,82
M10-235S-5UG
Über dieses Produkt
- SKU:
- M10-235S
- Zusätzliche Namen:
- Interleukin-17E
- Weitere Details:
- Mono-pegylated (with 20 kDa PEG) recombinant mouse leptin antagonist is one polypeptide chain containing 146 amino, an additional Ala at N-terminus and one molecule of PEG 20 kDa at its N-terminus, having an expected molecular mass of ~ 35.6 kDa as determined by MS. However due to enlarged hydrodymanic volume mouse pegylated leptin antagonist runs on the SDS-PAGE as 48 kDa protein and in gel-filtration on Superdex 200 as over 200 kDa protein. Mouse pegylated leptin antagonist half-life in circulation after SC injection was over 20 hours.. Mouse leptin antagonist was initially mutated, resulting in L39A/D40A/F41A mutant that was purified by proprietary chromatographic techniques according to Salomon et al (2006) Protein Expression and Purification 47, 128–136 and its pegylation is described in Elinav et al. Endocrinology 150:3083-91 (2009).
- Formulierung:
- lyophilized
- Host:
- Rabbit
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Room Temperature