CD80 / B7-1 Protein
Produktgrößen
100 ug
£553,00
600-060-L100-100UG
Über dieses Produkt
- SKU:
- 600-060-L100
- Zusätzliche Namen:
- B7 Protein; B71 Protein; Cd28l Protein; Cd80 Protein; Ly-53 Protein; Ly53 Protein; MIC17 Protein; TSA1 Protein
- Buffer:
- PBS
- Weitere Details:
- The B-lymphocyte activation antigen B7-1 (referred to as B7), also known as CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. As costimulatory ligands, B7-1 which exists predominantly as dimer and the related protein B7-2, interact with the costimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus constitute one of the dominant pathways that regulate T cell activation and tolerance, cytokine production, and the generation of CTL. The B7/CD28/CTLA4 pathway has the ability to both positively and negatively regulate immune responses. CD80 is thus regarded as promising therapeutic targets for autoimmune diseases and various carcinomas.
- Formulierung:
- lyophilized
- Molekulargewicht:
- 45 kDa (glycosylated)
- Reinheit:
- >95%
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins