VEGF-C
Produktgrößen
50 ug
£270,59
104-PABi10-50UG
Über dieses Produkt
- SKU:
- 104-PABi10
- Zusätzliche Namen:
- vascular endothelial growth factor C; Vegfc
- Anwendung:
- ELISA
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konjugat:
- Biotin
- Weitere Details:
- VEGF-C, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability. VEGF-C is expressed in various tissues, but is not produced in peripheral blood lymphocytes. It forms cell surfaced-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-C may play a role in the formation of the venous and lymphatic vascular systems. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis. Recombinant, fully processed rat VEGF-C is a 16-18 kDa non-disulfide linked homodimeric protein consisting of two 116 amino acid polypeptide chains. Due to glycosylation the protein migrates as a 20.0-22.0 kDa band under non-reducing condition.
- Formulierung:
- lyophilized
- Host:
- Rabbit
- Immunogen:
- Recombinant rat VEGF-C (RT #R20-015)
- Aufreinigung:
- Antigen-affinity purified
- Reaktivitäten:
- Rat
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C lyophilized. Aliquot. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Polyclonal Antibody