Lyve-1
Produktgrößen
100 ug
£270,59
103-PA50-100UG
200 ug
£411,76
103-PA50-200UG
Über dieses Produkt
- SKU:
- 103-PA50
- Zusätzliche Namen:
- Lyve1; Xlkd1; Lyve-1; Crsbp-1; 1200012G08Rik
- Anwendung:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- (#4A37)
- Klonalität:
- Polyclonal
- Weitere Details:
- LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.
- Formulierung:
- lyophilized
- Host:
- Rabbit
- Immunogen:
- Recombinant mouse soluble Lyve-1 (RT#S01-026)
- Aufreinigung:
- Protein A Purified
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C lyophilized. Aliquot. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Polyclonal Antibody