Wnt-5a
Produktgrößen
100 ug
£270,59
103-PA16-100UG
200 ug
£411,76
103-PA16-200UG
Über dieses Produkt
- SKU:
- 103-PA16
- Zusätzliche Namen:
- Wnt-5a; Wnt5a; Wnt 5a; Wnt
- Klonalität:
- Polyclonal
- Weitere Details:
- Wnt-5a is one of the most highly investigated non-canonical Wnts and has been implicated in almost all aspects of non-canonical Wnt signalling. In terms of cancer development, Wnt-5a has, until recently, lived in the shadow of its better-characterised relatives. This was largely because of its apparent inability to transform cells or signal through the canonical beta-catenin pathway that is so important in cancer, particularly colorectal cancer. Recent work in a wide range of human tumours has pointed to a critical role for Wnt-5a in malignant progression, but there is conflicting evidence whether Wnt-5a has a tumour-promoting or -suppressing role. Emerging evidence suggests that the functions of Wnt-5a can be drastically altered depending on the availability of key receptors. Hence, the presence or absence of these receptors may go some way to explain the conflicting role of Wnt-5a in different cancers.
- Formulierung:
- lyophilized
- Host:
- Rabbit
- Immunogen:
- Recombinant mouse Wnt-5a
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C lyophilized. Aliquot. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Polyclonal Antibody