IL-27
Produktgrößen
100 ug
£674,12
103-M407-100UG
Über dieses Produkt
- SKU:
- 103-M407
- Zusätzliche Namen:
- Il27; p28; Il30; IL-27; IL-27p28
- Anwendung:
- Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 11B29
- Klonalität:
- Monoclonal
- Weitere Details:
- Interleukin-27 (IL-27) is a heterodimeric group 2 receptor ligand molecule that belongs to the IL-6/IL-12 family of long type I cytokines. It is composed of EBI3 (EBV-induced gene 3), a 34 kDa glycoprotein that is related to the p40 subunit of IL-12 and IL-23, and p28, the 28 kDa glycoprotein that is related to the p35 chain of IL-12). The human EBI3 gene encodes a 229 amino acid (aa) precursor that contains a 20 aa signal peptide and 209 aa mature protein. The mature region contains two potential N-linked glycosylation sites, two fibronectin type III domains, and two pairs of conserved cysteine residues with a WSxWS-like motif that places the IL-27 molecule in the hematopoietin receptor family. Although p40, the EBI3 counterpart in IL-12, is known to form homodimers, there is no evidence to date that EBI3 also homodimerizes.
- Formulierung:
- lyophilized
- Host:
- Rat
- Immunogen:
- recombinant mouse IL-27
- Isotyp:
- IgG2
- Aufreinigung:
- Protein A/G Purified
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C lyophilized. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody