VEGFR-3/FLT-4
Produktgrößen
100 ug
£370,59
103-M36-100UG
Über dieses Produkt
- SKU:
- 103-M36
- Zusätzliche Namen:
- vascular endothelial growth factor receptor-3; Flt4; Chy; Flt-4; VEGFR3; VEGFR-3
- Anwendung:
- Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 7A3
- Klonalität:
- Monoclonal
- Weitere Details:
- VEGFR-3, also known as FLT4, is a member of the Tyr protein kinase family. The extracellular portion of VEGFR-3 contains 7 immunoglobulin (Ig)-like domains and the cytoplasmic portion contains a protein kinase domain. FLT4 regulates angiogenesis and lymphangiogenesis, its ligands are VEGF-C and D and its binding is mediated by the 2nd and 3rd Ig-like domains of FLT4. During fetal development VEGFR-3 is expressed on endothelial cells, however, in the adult mice, the vascular endothelial cells lose VEGFR-3 expression, but the lymphatic endothelium expresses it constitutively. In addition, VEGFR-3 expression can be induced in tumors with active angiogenesis.
- Formulierung:
- lyophilized
- Host:
- Rat
- Immunogen:
- recombinant mouse soluble FLT-4
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C lyophilized. Aliquot. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody