VEGF-B
Produktgrößen
100 ug
£674,12
101-M856-100UG
Über dieses Produkt
- SKU:
- 101-M856
- Zusätzliche Namen:
- vascular endothelial growth factor B; VEGFB; VRF; VEGFL
- Anwendung:
- Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 7B12
- Klonalität:
- Monoclonal
- Weitere Details:
- VEGF-B, a member of the VEGF family, is a potent growth and angiogenic cytokine. It promotes DNA synthesis in endothelial cells, helps regulate angiogenesis and vascular permeability, and inhibits apoptosis in certain smooth muscle cells and neurons. VEGF-B is expressed in all tissues except the liver. It forms cell surfaced-associated disulfide linked homodimers and can form heterodimers with VEGF-A. There are two known isoforms, formed by alternative splicing, which have been designated VEGF-B167 and VEGF-B186. Both forms have identical amino-terminal sequences encoding a "cysteine knot" like structural motif, but differ in their carboxyl-terminal domains. Both VEGF-B isoforms signal only through the VEGFR1 receptor. Recombinant human VEGF-B is a 38.0 kDa disulfide-linked homodimeric protein consisting of two 167 amino acid polypeptide chains.
- Formulierung:
- lyophilized
- Host:
- Mouse
- Immunogen:
- recombinant human VEGF-B 167
- Isotyp:
- IgG1
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody