Nidogen-1 (Entactin)
Produktgrößen
100 ug
£674,12
101-M816-100UG
Über dieses Produkt
- SKU:
- 101-M816
- Zusätzliche Namen:
- Nidogen-1, NID-1, Entactin
- Anwendung:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- translate.label.attr.clone:
- 2R33
- Klonalität:
- Monoclonal
- Weitere Details:
- Nidogen-1 (also entactin) is a 150 kDa, secreted, monomeric glycoprotein that serves as a major linking component of basement membranes. It is synthesized as a 1247 amino acid (aa) precursor with a 28 aa signal sequence and a 1219 aa mature protein. The molecule is modular in structure with five distinct regions. Functionally, G1 is reported to bind type IV collagen. The mucin region contains a short peptide that ligates alpha 3 beta 1 integrins. G2 interacts with perlecan, and an RGD motif in the rod-shaped segment serves as a binding site for alpha v beta 3 integrins. Finally, G3 is associated with laminin binding.
- Formulierung:
- lyophilized
- Host:
- Mouse
- Immunogen:
- Recombinant Human Nidogen-1/Entactin
- Isotyp:
- IgG1
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody