gp-130
Produktgrößen
100 ug
£674,12
101-M761-100UG
Über dieses Produkt
- SKU:
- 101-M761
- Zusätzliche Namen:
- IL6ST; CD130; GP130; CDW130; IL-6RB
- Anwendung:
- Block/Inhibit/Neutralise, Immunohistochemistry
- Buffer:
- PBS
- translate.label.attr.clone:
- 9X60
- Klonalität:
- Monoclonal
- Weitere Details:
- Gp130, the common signal transducing receptor component shared by the functional receptor complexes of the IL-6 family of cytokines, belongs to the classI cytokine receptor family. Binding of IL-6 or IL-11 to either the membrane-anchored or soluble IL-6 R or IL-11 R, respectively, initiates the association of IL-6 R (IL-11 R) with gp130. The complex then undergoes homodimerization and signal transduction. For other IL-6 family cytokines, such as LIF and OSM, signal transduction is similarly triggered by the heterodimerization of gp130 with LIFR or OSM R.
- Formulierung:
- lyophilized
- Host:
- Mouse
- Immunogen:
- recombinant human gp 130
- Isotyp:
- IgG1
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody