MCP-4
Produktgrößen
500 ug
£370,59
101-M76-500UG
Über dieses Produkt
- SKU:
- 101-M76
- Zusätzliche Namen:
- CCL13; NCC1; CKb10; MCP-4; NCC-1; SCYL1; SCYA13
- Anwendung:
- Block/Inhibit/Neutralise, ELISA, Western Blot
- Buffer:
- PBS
- Klonalität:
- Monoclonal
- Weitere Details:
- Monocyte Chemoattractant Protein-4 (MCP-4), is a CC chemokine that acts as a chemoattractant for monocytes, eosinophils and T cells and as an activator of basophils. Human MCP-4/CCL13 cDNA encodes a 98 amino acid residue precursor protein with a 23 amino acid residue hydrophobic signal peptide that is cleaved to yield an 8 kDa, 75 aa mature CCL13. Mature MCP-4 lacks any potential N-glycosylation sites and shares a pyroglutamate proline motif with other human MCP proteins. Human MCP-4 is most homologous to MCP-1, -3 and Eotaxin, exhibiting approximately 65-66% amino acid sequence identity. CCL13 or MCP-4 mRNA is expressed by a number of activated cell types, including endothelial cells, macrophages, bronchial epithelium and type II alveolar cells, and perhaps lymphocytes. The bioactivities of MCP-4 are mediated by the CC chemokine receptors CCR2 and CCR3.
- Formulierung:
- lyophilized from PBS
- Host:
- Mouse
- Immunogen:
- Recombinant Human MCP-4
- Isotyp:
- IgG1, kappa
- Aufreinigung:
- Protein A Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C lyophilized. Aliquot. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody