TFPI-2
Produktgrößen
100 ug
£674,12
101-M749-100UG
Über dieses Produkt
- SKU:
- 101-M749
- Zusätzliche Namen:
- TFPI2; PP5; REF1; TFPI-2
- Anwendung:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 9F6
- Klonalität:
- Monoclonal
- Weitere Details:
- Human TFPI is a physiological inhibitor of the extrinsic pathway of coagulation and functions in anticoagulation and anti-inflammation. It is a secreted protein with an N-terminal acidic region, three Kunitz (K) domains separated by two linker regions, and a C-terminal basic region. The first K domain inhibits coagulation factor VIIa complexed to tissue factor (TF). The second K domain inhibits factor Xa. The third K domain binds to heparin. The C-terminal basic region may have several functions. Human TFPI-2 is structurally similar to TFPI and is downregulated in several cancers.
- Formulierung:
- lyophilized
- Host:
- Mouse
- Immunogen:
- recombinant human TFPI-2
- Isotyp:
- IgG2
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C lyophilized. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody