Junctional adhesion molecule B (JAM-B)
Produktgrößen
100 ug
£674,12
101-M525-100UG
Über dieses Produkt
- SKU:
- 101-M525
- Zusätzliche Namen:
- JAM2; JAMB; CD322; JAM-B; VEJAM; PRO245; VE-JAM; C21orf43
- Anwendung:
- Block/Inhibit/Neutralise, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 4L28
- Klonalität:
- Monoclonal
- Weitere Details:
- Members of the junctional adhesion molecule (JAM) family are type I transmembrane glycoproteins of the immunoglobulin (Ig) superfamily that are localized in the tight junctions between endothelial or epithelial cells and appear to be involved in leukocyte transmigration. JAM-A, also known as platelet adhesion molecule 1 (PAM-1) and platelet F11 receptor, contains two V-type Ig-like domains, forms homodimers, and interacts with LFA-1. JAM-B (vasculo-endothelial or VE-JAM) and JAM-C each contain two Ig domains (one V-type and one C2-type), a cytoplasmic PDZ-binding motif and a PKC phosphorylation site. JAM-C interacts with MAC-1 and facilitates JAM-B interaction with integrin alpha 4 beta 1.
- Formulierung:
- lyophilized
- Host:
- Mouse
- Immunogen:
- recombinant human JAM-B
- Isotyp:
- IgG2
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C lyophilized. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody