HGF
Produktgrößen
100 ug
£674,12
101-M449-100UG
Über dieses Produkt
- SKU:
- 101-M449
- Zusätzliche Namen:
- HGF; SF; HGFB; HPTA; F-TCF; DFNB39
- Anwendung:
- Block/Inhibit/Neutralise, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 5D20
- Klonalität:
- Monoclonal
- Weitere Details:
- HGF is a mesenchymally derived potent mitogen for mature parenchymal hepatocyte cells and acts as a growth factor for a broad spectrum of tissues and cell types. HGF (or scatter factor) signals through a transmembrane tyrosine kinase receptor known as MET. Activities of HGF include induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and enhancement of neuron survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries. Human and murine HGF are cross-reactive. Human HGF is expressed as a linear 697 amino acid polypeptide precursor glycoprotein. Proteolytic processing of this precursor generates the biologically active form of HGF, which consists of two polypeptide chains (A Alpha-chain and B Beta-chain) held by a single disulfide bond resulting in formation of a biologically active heterodimer. The A Alpha-chain consists of 463 amino acid residues and four kringle domains. The B Beta-chain consists of 234 amino acid residues.
- Formulierung:
- lyophilized
- Host:
- Mouse
- Immunogen:
- Recombinant human HGF
- Isotyp:
- IgG1
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C lyophilized. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody