Coagulation Factor XI
Produktgrößen
100 ug
£674,12
101-M332-100UG
Über dieses Produkt
- SKU:
- 101-M332
- Zusätzliche Namen:
- F11; FXI
- Anwendung:
- Block/Inhibit/Neutralise, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 7C38
- Klonalität:
- Monoclonal
- Weitere Details:
- Coagulation Factor XI is synthesized in the liver and circulates in the plasma as a disulfide bond-linked dimer complexed with High Molecular Weight Kininogen. Factor XI is converted into active XIa either via the contact phase of blood coagulation or through Thrombin-mediated activation on the platelet surface. The resulting XIa converts Coagulation Factor IX into IXa, which subsequently activates Coagulation Factor X (Xa). Xa then can mediate Coagulation Factor II/Thrombin activation. Patients with factor XI deficiency are prone to excessive bleeding after hemostatic challenge.
- Formulierung:
- lyophilized
- Host:
- Mouse
- Immunogen:
- Human recombinant Coagulation factor XI
- Isotyp:
- IgG2
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody