Cathepsin E
Produktgrößen
100 ug
£674,12
101-M248-100UG
Über dieses Produkt
- SKU:
- 101-M248
- Zusätzliche Namen:
- CTSE; CATE
- Anwendung:
- Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 4F50
- Klonalität:
- Monoclonal
- Weitere Details:
- Cathepsin E is an intracellular aspartic protease of the pepsin family. Unlike Cathepsin D, another member of the same family and a lysosomal protease with relatively ubiquitous distribution, Cathepsin E is not a lysosomal enzyme and has a limited cell and tissue distribution. However, both Cathepsin D and E play an important role in the degradation of proteins, the generation of bioactive proteins, and antigen processing. Both enzymes are efficient in cleaving Swedish mutant of amyloid precursor protein (APP) at the B Beta site but show almost no reactivity with wildtype APP. Human Cathepsin E is synthesized as a precursor protein, consisting of a signal peptide (aa 1-17), a propeptide (aa 18-53), and a mature chain (aa 54-396).
- Formulierung:
- lyophilized
- Host:
- Mouse
- Immunogen:
- recombinant human Cathepsin-E
- Isotyp:
- IgG2
- Aufreinigung:
- Protein G Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -70[o]C lyophilized. Avoid freeze/thaw cycles.
- Typ:
- Antibody: Monoclonal Antibody