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Proteine und Peptide

TIGAR

Produktgrößen
5 ug
£178,82
100-429-5UG
25 ug
£307,06
100-429-25UG
Über dieses Produkt
SKU:
100-429
Zusätzliche Namen:
TP53-induced glyclysis and apoptosis regulator
Weitere Details:
TIGAR is a p53-inducible enzyme that catalyzes the hydrolysis of fructose-2-6 bisphosphate (F-2-6-BP) to fructose-6-phosphate and inorganic phosphate. F-2-6-BP is a powerful activator of 6-phosphofructose-1 kinase, the rate limiting enzyme of glycolysis. By lowering the intracellular level of F-2-6-BP, TIGAR expression leads to increased glucose processing via the pentose phosphate pathway, the major cellular source for NADPH. Recombinant human TIGAR expressed in E. coli is a 29.9 kDa protein containing 269 amino-acid residues.
Formulierung:
lyophilized
Molekulargewicht:
29.9 kDa
Reinheit:
> 95% by SDS-PAGE & HPLC analyses
Reaktivitäten:
Human
Sequenz:
ARFALTVVRH GETRFNKEKI IQGQGVDEPL SETGFKQAAA AGIFLNNVKF THAFSSDLMR TKQTMHGILE RSKFCKDMTV KYDSRLRERK YGVVEGKALS ELRAMAKAAR EECPVFTPPG GETLDQVKMR GIDFFEFLCQ LILKEADQKE QFSQGSPSNC LETSLAEIFP LGKNHSSKVN SDSGIPGLAA SVLVVSHGAY MRSLFDYFLT DLKCSLPATL SRSELMSVTP NTGMSLFIIN FEEGREVKPT VQCICMNLQD HLNGLTETR
Versandbedingungen:
Ambient
Lagerbedingungen:
Room Temperature
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins