BMP-10
Produktgrößen
2 ug
£178,82
100-405-2UG
10 ug
£307,06
100-405-10UG
Über dieses Produkt
- SKU:
- 100-405
- Zusätzliche Namen:
- BMP-10, Bone morphogenic protein 10
- translate.label.attr.clone:
- (#7F56)
- Weitere Details:
- Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-B Beta superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. BMP-10 plays a crucial role in the development of the embryonic heart by acting to stimulate and maintain cardiomyocyte proliferation.It can signal through various receptor complexes usually containing BMPR-1A, BMPR-1B, ALK1, ALK3, or ALK6. The interaction of BMP-10 with its specific receptors can induce signaling initiated by the phosphorylation of SMAD transcription factors, including SMAD1, SMAD5, or SMAD8, but can also induce SMAD independent processes. BMP-10 is structurally related to BMP-9, and both can inhibit endothelial cell proliferation and migration. Recombinant human BMP-10 is a 24.4 kDa homodimeric disulfide-linked protein consisting of two 108 amino acid subunits, which correspond to amino acid residues 317 to 424 of the full-length BMP-10 precursor.
- Formulierung:
- lyophilized
- Host:
- Mouse
- Molekulargewicht:
- 24.4 kDa
- Reinheit:
- >95%
- Reaktivitäten:
- Human
- Sequenz:
- NAKGNYCKRT PLYIDFKEIG WDSWIIAPPG YEAYECRGVC NYPLAEHLTP TKHAIIQALV HLKNSQKASK ACCVPTKLEP ISILYLDKGV VTYKFKYEGM AVSECGCR
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Room Temperature
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins