MIP-1 alpha (CCL3)
Produktgrößen
5ug
£178,82
100-073S-5UG
Über dieses Produkt
- SKU:
- 100-073S
- Zusätzliche Namen:
- CCL3; MIP1A; SCYA3; G0S19-1; LD78ALPHA; MIP-1-alpha
- Weitere Details:
- PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-AB is a 25.5 kDa disulfide-linked dimer, consisting of one A chain and one B chains (234 total amino acids).
- Formulierung:
- lyophilized
- Host:
- E. coli
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- Room Temperature