anti-p62 Protein C-terminus, guinea pig polyclonal antibody
Produktgrößen
100 ul
£384,00
GP62-C-100UL
Über dieses Produkt
- SKU:
- GP62-C
- Anwendung:
- Immunohistochemistry, Western Blot
- CE/IVD:
- RUO
- Klonalität:
- Polyclonal
- Weitere Details:
- Human 62 kDa (p62) protein, is present in intracytoplasmic inclusions (e.g. hyaline bodies) of hepatocellular carcinoma. p62 protein (also described as ubiqutin-binding protein; sequestosome 1; SQSTM1) has been found in many tissues and cells, including lymphoid cells, serving probably a common cellular signal transduction mechanism (e.g. ubiquitin-associated degradation and autophagy). The antiserum stains also neurofibrillary tangles in the brain of patients suffering from Alzheimer's disease. The GP62-C antibody is knockout validated (Waguri & Komatsu, 2009).Waguri, S. & Komatsu, M. Chapter 9 Biochemical and Morphological Detection of Inclusion Bodies in Autophagy-Deficient Mice. Methods in Enzymology 453, 181-196 (2009).
- Formulierung:
- Contains 0.09% sodium azide
- Host:
- Guinea Pig
- Immunogen:
- C-terminal domain (20 amino acids: C-NYD IGA ALD TIQ YSK HPP PL) of human p62 protein, coupled to KLH. This peptide sequence is identical in human, monkey, bovine, mouse, and rat.
- Aufreinigung:
- Stabilized antiserum
- Reaktivitäten:
- Bovine, Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Please refer to datasheet
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:GP62-C
