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Proteins and Peptides

Mouse PCSK9 recombinant protein (His-tagged, C-ter)

Product Sizes
50 ug
ARG70328-50UG
Academic Pricing
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About this Product
SKU:
ARG70328
Additional Names:
PC9; Subtilisin/kexin-like protease PC9; Proprotein convertase 9; Proprotein convertase subtilisin/kexin type 9; Neural apoptosis-regulated convertase 1; FH3; EC 3.4.21.-; HCHOLA3; NARC1; LDLCQ1; NARC-1
Application:
Cell-based/Functional Assay, SDS-PAGE
Buffer:
PBS (pH 7.4)
CE/IVD:
RUO
Extra Details:
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Immunogen:
PCSK9
Purity:
>97%
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C
Supplier:
Arigo Biolaboratories
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes