AZDye 405 Picolyl Azide
Produktgrößen
1 mg
£294,00
CCT-1308-1MG
5 mg
£769,00
CCT-1308-5MG
25 mg
£2175,00
CCT-1308-25MG
Über dieses Produkt
- SKU:
- CCT-1308
- Anwendung:
- Conjugation/Labeling
- Konjugat:
- AZDye™ 405
- Weitere Details:
- AZDye™ 405 Picolyl Azide is an advanced fluorescent probe that incorporates a copper-chelating motif to raise the effective concentration of Cu(I) at the reaction site to boost the efficiency of the CuAAC reaction, resulting in a faster and more biocompatible CuAAC labeling. Up to 40-fold increase of signal intensity, compared to conventional azides, was reported. In addition, the use picolyl azides instead of conventional azides allows for at least a tenfold reduction in the concentration of the copper catalyst without sacrificing the efficiency of labeling, significantly improving biocompatibility of CuAAC labeling protocol. In summary, the introduction of a copper-chelating motif into azide probe leads to a substantial increase in the sensitivity and reduced cell toxicity of CuAAC detection alkyne-tagged biomolecules. This will be of special value for the detection of low abundance targets or living system imaging. AZDye™ 405 is structurally similar and spectrally is almost identical to DyLight® 405, Alexa Fluor® 405, CF® 405S Dye, or any other sulfonated pyrene based fluorescent dyes.
- Molekulargewicht:
- 718.68 (protonated) 1022.26 (triethylammonium salt)
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C desiccated. Avoid freeze/thaw cycles.
- Hersteller:
- Vector - Click Chemistry Tools
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Fluorophores
- Datenblatt des Herstellers:AZDye-405-Picolyl-Azide
