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Proteine und Peptide

AZDye 568 Picolyl Azide

Produktgrößen
1 mg
£283,00
CCT-1292-1MG
5 mg
£709,00
CCT-1292-5MG
25 mg
£2175,00
CCT-1292-25MG
Über dieses Produkt
SKU:
CCT-1292
Anwendung:
Conjugation/Labeling
Konjugat:
AZDye™ 568
Weitere Details:
AZDye™ 568 Picolyl Azide is an advanced fluorescent probe that incorporates a copper-chelating motif to raise the effective concentration of Cu(I) at the reaction site to boost the efficiency of the CuAAC reaction, resulting in a faster and more biocompatible CuAAC labeling. Up to 40-fold increase of signal intensity, compared to conventional azides, was reported. In addition, the use picolyl azides instead of conventional azides allows for at least a tenfold reduction in the concentration of the copper catalyst without sacrificing the efficiency of labeling, significantly improving biocompatibility of CuAAC labeling protocol. In summary, the introduction of a copper-chelating motif into azide probe leads to a substantial increase in the sensitivity and reduced cell toxicity of CuAAC detection alkyne-tagged biomolecules. This will be of special value for the detection of low abundance targets or living system imaging. AZDye 568™ is a bright, and highly photostable, orange-fluorescent probe optimally excited by the 568 nm laser line on the Ar-Kr mixed-gas laser. This probe is water-soluble and its fluorescence is pH independent over a wide pH range. The brightness and photostability of this dye are best suited to direct imaging of low-abundance targets. AZDye™ 568 dye structurally is identical to Alexa Fluor® 568 Dye. Its absorption/emission spectra is a perfect match to spectra of many other fluorescent dyes based on sulfonated rhodamine core, including CF® 568 Dye, Alexa Fluor® 568.
Molekulargewicht:
897.25
Versandbedingungen:
Ambient
Lagerbedingungen:
-20[o]C desiccated. Avoid freeze/thaw cycles.
Hersteller:
Vector - Click Chemistry Tools
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Fluorophores