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Peanut Agglutinin (PNA), Fluorescein

Produktgrößen
5 mg
FL-1071-5MG
Über dieses Produkt
SKU:
FL-1071
Zusätzliche Namen:
Lectins & Glycobiology Reagents [Lectins ], Arachis hypogaea lectin, galactosyl (beta 1;3) N-acetylgalactosamine
Anwendung:
Immunofluorescence
Konjugat:
FITC
Weitere Details:
Peanut agglutinin binds preferentially to the T-antigen, a galactosyl (B Beta-1,3) N-acetylgalactosamine structure present in many glycoconjugates such as M and N blood groups, gangliosides, and many other soluble and membrane-associated glycoproteins and glycolipids. With certain exceptions, the receptor sequence for PNA is normally sialylated which prevents the lectin from binding to its receptor oligosaccharide (see Jacalin). Even sialic acid which is not bound directly to the receptor sugars may inhibit binding. The presence of calcium ions in diluents can enhance the binding of PNA to receptors, possibly by neutralizing the negative charges on sialic acid residues adjacent to the receptor sequence. Fluorescein labeled Peanut agglutinin has an appropriate number of fluorochromes bound to provide the optimum staining characteristics for this lectin. This conjugate is supplied essentially free of unconjugated fluorochromes. The excitation maximum is at 495 nm and the emission maximum is at 515 nm.
Versandbedingungen:
Ambient
Lagerbedingungen:
2-8[o]C
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Lectins