Tumor Necrosis Factor alpha (TNFa) (APC)
Produktgrößen
100ul
£1088,00
T9160-18A-APC-100UL
Über dieses Produkt
- SKU:
- T9160-18A-APC
- Anwendung:
- Immunohistochemistry, FLISA
- translate.label.attr.clone:
- 5E852
- Klonalität:
- Monoclonal
- Weitere Details:
- Tumor Necrosis Factor alpha (TNF-alpha) is a 17.3kD multi-functional pro-inflammatory cytokine primarily secreted by macrophages, but also produced by T and B lymphocytes, activated monocytes and fibroblasts. TNF-alpha exists in both a transmembrane and mature soluble form and has many biological properties, including activation of transcription factor NF-KappaB, the induction of apoptosis in various tumor cell lines and the stimulation of cell differentiation and proliferation under certain conditions. Studies have revealed a role for TNF-alpha in inflammation, septic shock, autoimmune disease and rheumatoid arthritis. Applications: Suitable for use in Immunohistochemistry, FLISA and Inhibition of biological activity of TNFa in different biological fluids. Other applications not tested. Recommended Dilutions: Immunohistochemistry: Formalin-fixed frozen tissues Optimal dilutions to be determined by the researcher. Hybridoma: X63.Ag8.653 myeloma cells with spleen cells of Balb/c mice. Storage and Stability: May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. Allophycocyanin (APC) is light sensitive. Note: Applications are based on unconjugated antibody.
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to human TNF-alpha.
- Isotyp:
- IgG1
- Physischer Zustand:
- Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).
- Reinheit:
- Purified by Protein A affinity chromatography.
- Versandbedingungen:
- Blue Ice
- Spezifität:
- Recognizes human TNFa. Effective in the inhibiting the biological activity of recombinant and naturtal TNFa.
- Quelle:
- human
- Lagerbedingungen:
- 4[o]C Do Not Freeze
- Hersteller:
- United States Biological
- Typ:
- Antibodies:Monoclonal Antibody