TLR7 (Toll Like Receptor 7, TLR-7, PRO285, UNQ248) (PE)
Produktgrößen
100Tests
£1010,00
T8050-71Q-100TESTS
Über dieses Produkt
- SKU:
- T8050-71Q
- Anwendung:
- Flow Cytometry
- translate.label.attr.clone:
- 9L859
- Klonalität:
- Monoclonal
- Weitere Details:
- Toll-like receptor 7 (TLR7) is a 120kD (predicted, unglycosylated) type I transmembrane glycoprotein and member of the Toll-like receptor family. Human TLR7 is synthesized as a 1049aa precursor that contains a 26aa signal sequence, an 803aa extracellular domain (ECD), a 21aa transmembrane sequence, and a 189aa cytoplasmic domain. Mature human TLR7 is 81% aa identical to mature mouse TLR7. TLR7 is detected in brain, placenta, spleen, stomach, small intestine, lung, and in plasmacytoid pre-dendritic cells. Functionally, TLR7 participates in the innate immune response to microbial agents. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 10ul labels 10e6 cells Optimal dilutions to be determined by the researcher. Hybridoma: Mouse myeloma cells with B cells from a mouse. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to Met360-Leu516 from human toll-like receptor 7, expressed in E. coli. Species Sequence Homology: mouse, 81%
- Isotyp:
- IgG2a
- Physischer Zustand:
- Supplied as a liquid in saline, 0.5% BSA, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE).
- Reinheit:
- Purified by Protein A affinity chromatography from hybridoma culture supernatant.
- Versandbedingungen:
- Blue Ice
- Spezifität:
- Recognizes human TLR7.
- Quelle:
- human
- Lagerbedingungen:
- 4[o]C Do Not Freeze
- Hersteller:
- United States Biological
- Typ:
- Antibodies:Monoclonal Antibody