Smac, Recombinant, Human (DIABLO, Direct IAP Binding Protein of Low Pi, Second Mitochondrial Activator of Cell Death)
Produktgrößen
100ug
£651,00
S1014-48H-100UG
Über dieses Produkt
- SKU:
- S1014-48H
- Weitere Details:
- Smac/Diablo is one of the proapoptotic proteins. Smac promotes caspase activation in the cytochrome c/Apaf-1/caspase-9 pathway by binding to inhibitor of apoptosis proteins (IAPs) and removing their inhibitory activity. Recombinant human Smac fused to T7-tag at N-terminal domain was expressed in E. coli and purified by conventional chromatography techniques. Source: Recombinant protein corresponding to aa56-239 from human Smac, fused to T7-tag at N-terminal domain, expressed in E.coli. Molecular Weight: ~22kD (MALDI-TOF) Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Amino Acid Sequence: MASMTGGQQM GRGSMAVPIA QKSEPHSLSS EALMRRAVSL VTDSTSTFLS QTTYALIEAI TEYTKAVYTL TSLYRQYTSL LGKMNSEEED EVWQVIIGAR AEMTSKHQEY LKLETTWMTA VGLSEMAAEA AYQTGADQAS ITARNHIQLV KLQVEEVHQL SRKAETKLAE AQIEELRQKT QEEGEERAES EQEAYLRED Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Molekulargewicht:
- 22
- Physischer Zustand:
- Supplied as a liquid in 20mM Tris pH 7.5.
- Reinheit:
- ≥95% by SDS-PAGE
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- United States Biological
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules