RhoB (ARH6, ARHB, RHOH6, Ras homolog family member B, ARH6, Aplysia Ras-related homolog 6, ARHB, RhoH6)
Produktgrößen
100ug
£659,00
R1998-10H-100UG
Über dieses Produkt
- SKU:
- R1998-10H
- Anwendung:
- Western Blot
- translate.label.attr.clone:
- 8C288
- Klonalität:
- Monoclonal
- Weitere Details:
- RhoB mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Host:
- Mouse
- Immunogen:
- Partial recombinant protein corresponding to human RhoB
- Isotyp:
- IgG1
- Physischer Zustand:
- Supplied as a liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.
- Reinheit:
- Purified by Protein G affinity chromatography from hybridoma culture supernatant
- Versandbedingungen:
- Blue Ice
- Spezifität:
- Recognizes human RhoB.
- Quelle:
- human
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- United States Biological
- Typ:
- Antibodies:Monoclonal Antibody