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Antikörper

LAG3 (Lymphocyte Activation Gene 3 Protein, LAG-3, Protein FDC, CD223, FDC)

Produktgrößen
100ug
£1010,00
L1050-61R-100UG
Über dieses Produkt
SKU:
L1050-61R
Anwendung:
Flow Cytometry
translate.label.attr.clone:
12K124
Klonalität:
Monoclonal
Weitere Details:
LAG-3 is a member of the immunoglobulin superfamily (IgSF). The mature LAG-3 protein is a 496aa membrane protein with a 421aa extracellular region which contains four IgSF domains, a 21aa transmembrane region and a 54aa cytoplasmic region. LAG-3 shares <20% aa sequence homology with CD4, but has similar structure and binds to MHC class II with higher affinity. The mouse LAG-3 extracellular region shares 69% aa sequence identity with human LAG-3. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 2.5ug labels10e6 cells Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Host:
Rat
Immunogen:
Recombinant preotein corresponding to Ser23-Leu442 from mouse LAG-3 expressed in NS0 cell line.
Isotyp:
IgG2b
Physischer Zustand:
Supplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 200ul sterile PBS.
Reinheit:
Purified by Protein G affinity chromatography from hybridoma culture supernatant.
Versandbedingungen:
Blue Ice
Spezifität:
Recognizes mouse LAG-3. Does not react with recombinant human LAG-3.
Quelle:
mouse
Lagerbedingungen:
-20[o]C
Hersteller:
United States Biological
Typ:
Antibodies:Monoclonal Antibody