Ectonucleotide Pyrophosphatase, Phosphodiesterase 7 (ENPP-7, Gm254, Alk-SMase, Enpp7)
Produktgrößen
100ug
£812,00
E3224-08-100UG
Über dieses Produkt
- SKU:
- E3224-08
- Anwendung:
- Western Blot
- translate.label.attr.clone:
- 11D63
- Klonalität:
- Monoclonal
- Weitere Details:
- SENPP-7 (ectonucleotide pyrophosphatase/phosphodiesterase 7), also known as alkaline sphingomyelinase (Alk-SMase)is a 60kD GPI-linked membrane glycoprotein expressed in the intestines and in human bile. It shares 30%-36% homology with the NPP family, but is unrelated to neutral or acid SMase. ENPP-7 hydrolyzes dietary sphingomyelin to form ceramide and phosphorylcholine, and may also hydrolyze and inactivate platelet-activating factor (PAF). It is downregulated in some human colorectal carcinomas. The 416aa mature human ENPP-7 shares 80% and 82% aa identity with mouse and rat ENPP-7, respectively. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 2ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to Pro23-Ser439 from human ENPP-7 expressed in NSO cells.
- Isotyp:
- IgG2b
- Physischer Zustand:
- Supplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 200ul sterile PBS.
- Reinheit:
- Purified by Protein G affinity chromatography.
- Versandbedingungen:
- Blue Ice
- Spezifität:
- Recognizes human ENPP-7. Does not react with recombinant human ENPP-2, recombinant human ENPP-5 or recombinant mouse ENPP-7.
- Quelle:
- human
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- United States Biological
- Typ:
- Antibodies:Monoclonal Antibody