CXCR4 (Fusin, LESTR, HUMSTR, C-X-C Chemokine Receptor 4, CD184)
Produktgrößen
100ug
£767,00
C8350-06C-100UG
Über dieses Produkt
- SKU:
- C8350-06C
- Anwendung:
- Flow Cytometry, Immunohistochemistry
- translate.label.attr.clone:
- 7H160
- Klonalität:
- Monoclonal
- Weitere Details:
- CXCR4, also known as fusin, is a 7TM G protein-linked chemokine receptor. CXCR4 is expressed on B cells, monocytes, CD4 + T cells, colonic epithelial cells, and astrocytes and binds SDF-1/CXCL12. CXCR4 is upregulated on mammary tumors. CXCR4, in cooperation with CD134 and heparan sulfate proteoglycans, functions as a co-receptor for feline immunodeficiency virus (FIV) entry into cells. Feline CXCR4 shares 97%, 95%, 88%, and 90% aa sequence identity with canine, human, mouse, and rat CXCR4, respectively. Applications: Suitable for use in Flow Cytometry, Immunohistochemistry and ELISA. Other applications not tested. Recommended Dilution: Flow Cytometry: 25ug/ml Immunohistochemistry: 25ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Host:
- Mouse
- Immunogen:
- HEK293 cells transfected with feline CXCR4, Met1-Ser353.
- Isotyp:
- IgG2a
- Physischer Zustand:
- Supplied as a lyophilized powder from a 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with 1ml sterile PBS.
- Reinheit:
- Purified by Protein G affinity chromatography.
- Versandbedingungen:
- Blue Ice
- Spezifität:
- Recognizes feline CXCR4. Stains feline CXCR4 transfectants but not irrelevant transfectants.
- Quelle:
- feline
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- United States Biological
- Typ:
- Antibodies:Monoclonal Antibody